•Wright’s stain demonstrates tumor cells with vacuolated cytoplasm.
• Oil red O stain shows numerous orange-red dot-like deposits within the cytoplasmic vacuoles
•Wright’s stain demonstrates tumor cells with vacuolated cytoplasm.
• Oil red O stain shows numerous orange-red dot-like deposits within the cytoplasmic vacuoles.
•Non specific esterase- predominantly stains monocytes
• Chloroacetate esterase and MPO - predominantly stains cells of myeloid series
Burkitts lymphoma is characterised by diffuse, monotonous proliferation of lymphoma cells along with tingible body macrophages forming a “starry sky appearance “ or a “ moth eaten appearance”
The cytoplasmic vacuoles of the lymphoma cells contain lipid which will give a positive Oil Red O reaction